TBXAS1 Polyclonal Antibody Store at -20°C
SKU: E-AB-11128-200
TBXAS1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11128 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human TBXAS1 |
| Abbre | TBXAS1 |
| Synonyms | BDPLT14, CYP5, CYP5A1, Cytochrome P450, Cytochrome P450 5A1, FLJ52771, GHOSAL, Platelet cytochrome P450 subfamily V, THAS, Tbxas1, Thromboxane A synthase 1 (platelet, Thromboxane A synthase 1 (platelet), cytochrome P450, family , family 5, polypeptide 1, subfamily A |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum membrane. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.