STK4 Polyclonal Antibody Store at -20°C
SKU: E-AB-13112-200
STK4 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13112 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human STK3/STK4 |
| Abbre | STK3/STK4 |
| Synonyms | Kinase responsive to stress, Krs2, MST-1, MST1, Mammalian STE20 like protein kinase 1, Mammalian STE20-like protein kinase 1, Mammalian sterile 20 like 1, Serine/th, Serine/threonine kinase 4, Serine/threonine protein kinase Krs 2, Serine/threonine-protein kinase 4 |
| Swissprot | |
| Calculated MW | 56 kDa |
| Cellular Localization | Cytoplasm. Nucleus. The caspase-cleaved form cycles between the nucleus and cytoplasm. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK subfamily.The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily.Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation.