SOCS2 Polyclonal Antibody Store at -20°C
SKU: E-AB-14356-200
SOCS2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14356 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SOCS2 |
| Abbre | SOCS2 |
| Synonyms | CIS 2, CIS-2, CIS2, Cish 2, Cish2, Cytokine inducible SH2 protein 2, Cytokine-inducible SH2 protein 2, SOCS 2, SOCS-2, SOCS2, SSI 2, SSI-2, SSI2, STAT induced STAT inhibitor 2, STAT-induced STAT inhibitor 2, STATI 2, STATI2, Socs2, Suppressor of cytokine signaling 2 |
| Swissprot | |
| Cellular Localization | Cytosol, Other locations: cytoplasm. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.