SMNDC1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52865-200
SMNDC1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52865 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human SMNDC1 |
| Abbre | SMNDC1 |
| Synonyms | survival of motor neuron-related , 30 kDa splicing factor SMNrp, MGC106917, MGC112663, SMN related protein, SMN-related protein, SMNR, SPF30, Splicing factor 30, Survival motor neuron domain containing 1, Survival motor neuron domain containing protei, smndc1 |
| Swissprot | |
| Cellular Localization | Nucleus speckle. Nucleus>Cajal body. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.