SEPT1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52732-200
SEPT1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52732 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human SEPT1 |
| Abbre | SEPT1 |
| Synonyms | DIFF6, Differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase), LARP, MGC20394, PNUTL3, Peanut like protein 3, Peanut-like protein 3, SEP1, SEPT1, Septin 1, Septin-1, Serologically defined breast, Serologically defined breast cancer antigen NY BR 24 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cytoplasm>cytoskeleton. Cytoplasm>cytoskeleton>centrosome. Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis. |
| Concentration | 1.02 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Immunology, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined.SEPT1 (Septin 1) is a Protein Coding gene. Among its related pathways are Aurora B signaling and Bacterial invasion of epithelial cells. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is SEPT4.