RIDA Polyclonal Antibody Reactivity Human
SKU: E-AB-53037-200
RIDA Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53037 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RIDA |
| Abbre | RIDA |
| Synonyms | 14.5 kDa translational inhibitor protein, 2-iminobutanoate/2-iminopropanoate deaminase, Heat responsive protein 12, Heat-responsive protein 12, Hrsp12, PSP, Perchloric acid soluble protein, Reactive intermediate imine deaminase A homolog, Ribonuclease UK114, p14.5 |
| Swissprot | |
| Calculated MW | 14 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Nucleus. Mostly cytoplasmic but, in less differentiated cells occasionally nuclear. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase. May also function as an endoribonuclease, cleaving mRNA phosphodiester bonds of single-stranded RNA (By similarity). Thereby, may inhibit protein translation (PubMed:8973653).