RICTOR Polyclonal Antibody Store at -20°C
SKU: E-AB-14684-200
RICTOR Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14684 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human RICTOR |
| Abbre | RICTOR |
| Synonyms | AVO3, AVO3 homolog, DKFZp686B11164, KIAA1999, Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae), MGC39830, PIA, Pianissimo, RICTR, RPTOR ind, Rapamycin insensitive companion of mTOR, Rapamycin-insensitive companion of mTOR, Rictor, hAVO3, mAVO3 |
| Swissprot | |
| Cellular Localization | Cytosol, Other locations: TORC2 complex. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Rapamycin-insensitive companion of mTOR is a protein that in humans is encoded by the RICTOR gene.RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals.mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive.mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.