Recombinant Mouse Frizzled 1/FZD1 Protein (Fc Tag)
SKU: PKSM041027-50
Recombinant Mouse Frizzled 1/FZD1 Protein (Fc Tag)
| SKU # | PKSM041027 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | Frizzled homolog 1, Frizzled-1, Fz-1, Fzd1, mFz1 |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Val69-His248 |
| Accession | O70421 |
| Calculated Molecular Weight | 46.8 kDa |
| Observed Molecular Weight | 55-70 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.