Recombinant Mouse FCRL1 Protein (aa 17-219, His Tag)
SKU: PKSM041196-50
Recombinant Mouse FCRL1 Protein (aa 17-219, His Tag)
| SKU # | PKSM041196 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | BXMAS1-like protein 1, Bxmas1, Bxmh1, Bxmh1b, CD307a, Fc receptor homolog 1, Fc receptor-like protein 1, FcR-like protein 1, FcRH1, FcRL1, Fcrh1, Fcrh1l, Fcrh1s, IFGP family protein 1, Ifgp1 Protein, mBXMH1, mIFGP1, moFcRH1 |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Ala17-Ser219 |
| Accession | BAC30017.1 |
| Calculated Molecular Weight | 22.5 kDa |
| Observed Molecular Weight | 40-60 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Mouse Fc receptor-like protein 1 (FCRL1) is a single-pass type I membrane protein. It is expressed in B-cells at the various stages of differentiation. Mouse FCRL1 consists of a 203 amino acid (aa) extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 103 aa cytoplasmic domain with two immunotyrosine activation motifs (ITAMs). FCRL1 is likely not a receptor for immunoglobulin. It may function as an activating coreceptor in B-cells and B-cells differentiation.