Recombinant Mouse Cystatin 7/CST7 Protein (His Tag)
SKU: PKSM040999-50
Recombinant Mouse Cystatin 7/CST7 Protein (His Tag)
| SKU # | PKSM040999 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CMAP, Cst7, Cystatin-7, Cystatin-F, Cystatin-like Metastasis-Associated Protein, Leukocystatin |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Ala19-Gln144 |
| Accession | O89098 |
| Calculated Molecular Weight | 15.4 kDa |
| Observed Molecular Weight | 18 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a biomarker for both liver metastasis and inflammatory lung disorders. Mouse Cystatin F inhibits papain and cathepsin L but with affinities lower than other cystatins. It may play a role in immune regulation through inhibition of a unique target in the hematopoietic system.