Recombinant Mouse CXCL10 protein(N-His)(active)
SKU: PKSM041503-100
Recombinant Mouse CXCL10 protein(N-His)(active)
| SKU # | PKSM041503 |
| Expression Host | E.coli |
Description
| Synonyms | IFNB1, Type I Interferon |
| Species | Mouse |
| Expression Host | E.coli |
| Sequence | Ile 22-Pro 98 |
| Accession | P17515 |
| Calculated Molecular Weight | 9.5 kDa |
| Observed Molecular Weight | 11-17 kDa |
| Tag | N-His |
| Bio-activity | Measure by its ability to chemoattract BaF3 cells transfected with human CXCR3.The ED50 for this effect is <0.2 μg/mL. |
Properties
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types; such as monocytes; endothelial cells and fibroblasts; in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles; such as chemoattraction for activated T-lymphocytes; inhibition of angiogenesis; and antitumor activity.