Recombinant Human PRG2/BMPG Protein (His Tag)
SKU: PKSH032124-50
Recombinant Human PRG2/BMPG Protein (His Tag)
| SKU # | PKSH032124 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | BMPG, Bone Marrow Proteoglycan, EMBP, Eosinophil Granule Major Basic Protein, MBP, PRG2, Pregnancy-Associated Major Basic Protein, Proteoglycan 2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Leu17-Tyr222 |
| Accession | AAH05929.1 |
| Calculated Molecular Weight | 24.6 kDa |
| Observed Molecular Weight | 33 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Reconstitution | Not Applicable |
Background
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity reactions.