Recombinant Human Ig lambda constant 2 (C-6His)
SKU: PKSH034054-50
Recombinant Human Ig lambda constant 2 (C-6His)
| SKU # | PKSH034054 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | IGLC, IGLC2, Ig Lambda C Domain, Ig lambda constant 2, Immunoglobulin Lambda Constant 2, MGC20392, MGC45681, immunoglobulin lambda constant 2 (Kern-Oz- marker) |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gly1-Ser106 |
| Accession | P0DOY2 |
| Calculated Molecular Weight | 12.1 kDa |
| Observed Molecular Weight | 16 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. IGLC2 is 105 amino acids (aa) in length. It contains one Ig-like domain (aa 7-100) and generates a disulfide bond with an IgH chain via Cys104.