Recombinant Human Annexin A3/ANXA3 Protein
SKU: PKSH032075-50
Recombinant Human Annexin A3/ANXA3 Protein
| SKU # | PKSH032075 |
| Expression Host | E.coli |
Description
| Synonyms | 2-cyclic phosphate 2-phosphohydrolase, 35-alpha calcimedin, ANX3, Annexin III, Annexin-3, Inositol 1, Lipocortin III, PAP-III, Placental anticoagulant protein III |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Asp323 |
| Accession | P12429 |
| Calculated Molecular Weight | 36.4 kDa |
| Observed Molecular Weight | 33 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Annexin A3（ANXA3）contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. ANXA3 is Inhibitor of phospholipase A2 and cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. it also also play a role in anti-coagulant properties.