RAC2 Polyclonal Antibody Host Rabbit
SKU: E-AB-40245-200
RAC2 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40245 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human Ras-related C3 botulinum toxin substrate 2 protien |
| Abbre | RAC2 |
| Synonyms | small GTP binding protein Rac2), EN 7, GX, HSPC 022, HSPC022, RAC 2, Ras related C3 botulinum toxin substrate 2, Ras related C3 botulinum toxin substrate 3, Ras related C3 botulinum toxin substrate 3 (rho family, Rho family small GTP binding protein Rac, p21 Rac 2 |
| Swissprot | |
| Cellular Localization | Cytoplasm |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.