PSMD9 Polyclonal Antibody Store at -20°C
SKU: E-AB-14324-200
PSMD9 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14324 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PSMD9 |
| Abbre | PSMD9 |
| Synonyms | 26S proteasome non ATPase regulatory subunit 9, 26S proteasome non-ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27, Homolog of rat Bridge 1, MGC8644, Proteasome (prosome macropain) 26S subunit non ATPase 9, Proteasome 26S non ATPase regul, p27 |
| Swissprot | |
| Calculated MW | 25 kDa |
| Cellular Localization | Cytosol, Nucleus, nucleoplasm, nucleus, Other locations: cytoplasm, proteasome regulatory particle. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.