PRAME Polyclonal Antibody
SKU: E-AB-52200-200
PRAME Polyclonal Antibody
| SKU # | E-AB-52200 |
| Reactivity |
Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PRAME |
| Abbre | PRAME |
| Synonyms | 4930534P07Rik, CT130, Cancer/testis antigen 130, MAPE, Melanoma antigen preferentially expressed in tumors, OIP 4, OIP-4, OIP4 , OPA interacting protein 4, OPA-interacting protein 4, Opa interacting protein OIP4, PRAME, Preferentially expressed antigen in melan |
| Swissprot | |
| Cellular Localization | Nucleus. Cell membrane. |
| Concentration | 1.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Tags and Cell markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:250 |
Background
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.