PLA2G2A Polyclonal Antibody Reactivity Human
SKU: E-AB-53043-200
PLA2G2A Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53043 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PLA2G2A |
| Abbre | PLA2G2A |
| Synonyms | group IIA (plat, GIIC sPLA2, Group IIA phospholipase A2, MOM1, NPS-PLA2, Non-pancreatic secretory phospholipase A2, OTTHUMP00000002786, PA2GA, Phosphatidylcholine 2-acylhydrolase 2A, Phospholipase A2, Phospholipase A2 group IIA, membrane associated |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.