Phospho-PKC Delta (Thr507) Polyclonal Antibody
SKU: E-AB-20968-200
Phospho-PKC Delta (Thr507) Polyclonal Antibody
| SKU # | E-AB-20968 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human PKC δ around the phosphorylation site of Thr507 |
| Synonyms | CVID9, D14Ertd420e, KPCD, Kinase PKC delta, MAY 1, MAY1, MGC49908, PCKd, PKC d, PKC delta, PKCD, PKCdelta, PRKC D, PRKC delta, Prkcd, Protein Kinase C delta, Protein Kinase Cdelta, Protein kinase C delta VIII, Protein kinase C delta type, Tyrosine, nPKC delta, nPKC-delta |
| Swissprot | |
| Calculated MW | 77 kDa |
| Observed MW | 78 kDa |
| Cellular Localization | Cytoplasm. Membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.