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Phospho-JAK1 (Tyr1022) Polyclonal Antibody

SKU: E-AB-20913-200

  • $ 55995
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Phospho-JAK1 (Tyr1022) Polyclonal Antibody

 

SKU # E-AB-20913
Reactivity Human,  Mouse,  Rat
Host Rabbit
Applications WB,  IHC-p,  IF

 

Product Details

Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC-p,  IF
Clonality Polyclonal
Immunogen Synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022
Abbre JAK1 (phospho Tyr1022)
Synonyms JAK 1,  JAK 1A,  JAK 1B,  JAK-1,  JAK1,  JAK1A,  JAK1B,  JTK3,  Janus kinase 1,  Janus kinase 1 (a protein tyrosine kinase),  Tyrosine protein kinase JAK 1,  Tyrosine protein kinase JAK1,  Tyrosine-protein kinase JAK1
Swissprot
Calculated MW 132 kDa
Observed MW 132 kDa
Cellular Localization Endomembrane system. Wholly intracellular, possibly membrane associated.
Tissue Specificity Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

 

Related Reagents

Applications Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:50-1:200

 

Background   

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.