PFKP Polyclonal Antibody Store at -20°C
SKU: E-AB-14704-200
PFKP Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14704 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PFKP |
| Abbre | PFKP |
| Synonyms | 1200015H23Rik, 6 phosphofructokinase, 6 phosphofructokinase type C, 6-phosphofructokinase, 6-phosphofructokinase type C, 9330125N24Rik, FLJ40226, K6PP, MGC105718, PFK, PFK C, PFK-C, PFKF, PFKP, Phospho, Phosphofructo 1 kinase isozyme C, fibroblast type, platelet type |
| Swissprot | |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, extracellular matrix, Nucleus, Other locations: cytoplasm, membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.