PDIA4 Polyclonal Antibody Reactivity Human
SKU: E-AB-52766-200
PDIA4 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52766 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PDIA4 |
| Abbre | PDIA4 |
| Synonyms | Calcium binding protein intestinal related, EPR70, EPR72, ER protein 70, ER protein 72, ERP 70, ERp 72, ERp-72, ERp70, ERp72, Endoplasmic reticulum resident protein 70, Endoplasmic reticulum resident protein 72, PDIA 4, PDIA4, PDIR, Pdia4, Protein disulfide isomerase A4 |
| Swissprot | |
| Calculated MW | 73 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
PDIA4(Protein disulfide-isomerase A4) is also named as ERP70,ERP72 and belongs to the protein disulfide isomerase family. It catalyzes the rearrangement of -S-S- bonds in proteins. ERp72 is a soluble protein localized in the ER lumen and contains the COOH-terminal retention signal,KEEL. There are 6 cysteine residues in the amino acid sequences of mouse and human ERp72. All of the cysteine residues occur in the internal thioredoxin motif,CGHC. The full length protein has a signal peptide with 20 amino acid.