PDE6D Polyclonal Antibody Reactivity Human
SKU: E-AB-53046-200
PDE6D Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53046 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PDE6D |
| Abbre | PDE6D |
| Synonyms | 5''-cyclic phosphodiesterase subunit delta, GMP PDE delta, GMP-PDE delta, PDE 6, PDE 6D, PDE D, PDE6, PDE6D, PDED, Phosphodiesterase 6D cGMP specific, Phosphodiesterase 6D cGMP specific rod delta, Protein p17, Retinal rod photoreceptor cGMP phosphod, p17 protein |
| Swissprot | |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.