NOS3 Monoclonal Antibody
SKU: E-AB-22088-200
NOS3 Monoclonal Antibody
| SKU # | E-AB-22088 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein |
| Abbre | eNOS |
| Synonyms | Constitutive NOS, EC NOS, EC-NOS, Endothelial NOS, Endothelial nitric oxidase synthase, Endothelial nitric oxide synthase, Endothelial nitric oxide synthase 3, Nitric oxide syntha, Nitric oxide synthase 3, Nitric oxide synthase 3 (endothelial cell), cNOS, eNOS, ecNOS |
| Swissprot | |
| Calculated MW | 133 kDa |
| Observed MW | 130 kDa |
| Cellular Localization | Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle and which is favored by interaction with NOSIP and results in a reduced enzymatic activity. |
| Tissue Specificity | Platelets, placenta, liver and kidney |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience |
| Clone No. | 6G3 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-2000 |
Background
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.