NEK2 Polyclonal Antibody Store at -20°C
SKU: E-AB-10922-200
NEK2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10922 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NEK2 |
| Abbre | NEK2 |
| Synonyms | HSPK 21, HsPK21, NEK 2, NEK2, NEK2A, NIMA (never in mitosis gene a) related kinase 2, NIMA related kinase 2, Never in mitosis A-related kinase 2, NimA like protein kinase 1, NimA related protein kinase 2, NimA-like protein kinase 1, NimA-related protein kinase |
| Swissprot | |
| Calculated MW | 52 kDa |
| Cellular Localization | Cytoplasm, Predominantly cytoplasmic, Nucleus>nucleolus, Has a nucleolar targeting/ retention activity via a coiled-coil domain at the C-terminal end and Nucleus, Chromosome>centromere, Chromosome>centromere>kinetochore, Co-localizes with SGOL1 and MAD1L1 at the kinetochore, Not associated with kinetochore in the interphase but becomes associated with it upon the breakdown of the nuclear envelope. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.