NDUFB11 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-52254-200
NDUFB11 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-52254 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | NDUFB11 |
| Synonyms | CI ESSS, Complex I ESSS, ESSS, FLJ20494, MGC111182, NADH deh, NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11, NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11 17.3kDa, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, complex I NP17.3 subunit |
| Swissprot | |
| Calculated MW | 17 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Mitochondrion inner membrane. |
| Concentration | 1.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal transduction, Tags & Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:300 |
Background
Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.