NANOS2 Polyclonal Antibody
SKU: E-AB-11419-200
NANOS2 Polyclonal Antibody
| SKU # | E-AB-11419 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NANOS2 |
| Abbre | NANOS2 |
| Synonyms | NANO2, NANOS2, NOS-2, NOS2, Nanos homolog 2, Nanos homolog 2 Drosophila |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cytoplasm>P-body. Cytoplasm>perinuclear region. Localizes at P-bodies during gonocyte development (By similarity). More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Nanos2, also known as NOS2, is a 138 amino acid protein that contains one nanos-type zinc finger.The nanos-type zinc finger is comprised of two C2HC motifs, each of which are capable of binding one molecule of zinc and each of which work in tandem to play essential roles in translational regulation events.Expressed specifically in male germ cells, Nanos2 is essential for spermatogonia formation and is required to support the self-renewal, proliferation and overall development of proximal germ cells.Additionally, Nanos2 is thought to regulate the translation of target mRNAs, possibly by associating with the 3’-UTR of select transcripts.