MSE PRO (1R,3R,5S)-8-Azabicyclo[3.2.1]octan-3-ol hydrochloride, ≥98.0% Purity

MSE PRO™ (1R,3R,5S)-8-Azabicyclo[3.2.1]octan-3-ol hydrochloride, ≥98.0% Purity

MSE PRO™ (1R,3R,5S)-8-Azabicyclo[3.2.1]octan-3-ol hydrochloride is a chiral bicyclic compound containing a nitrogen atom and a hydroxy group, existing as the hydrochloride salt. The presence of the hydroxy group and the rigid bicyclic ring system make this compound a versatile synthetic intermediate for the preparation of various nitrogen-containing heterocyclic compounds and pharmaceutically active molecules. As a chiral building block, it can be employed in enantioselective synthesis, enabling the construction of optically pure drugs, agrochemicals, and other biologically active compounds where stereochemical purity is crucial for potency and selectivity.

 MSE Supplies offers various N-heterocyclic drug small molecules and other chemical reagents. Please contact us for bulk orders.

Technical Specifications:

References:

[1] Varty, G. B., Lu, S. X., Morgan, C. A., Cohen-Williams, M. E., Hodgson, R. A., Smith-Torhan, A., ... & Carey, G. J. (2008). The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis (2-methylphenyl) methyl]-3-phenyl-8-azabicyclo [3.2. 1] octan-3-ol (SCH 221510). Journal of Pharmacology and Experimental Therapeutics, 326(2), 672-682.

[2] Millard, M., Kilian, J., Ozenil, M., Mogeritsch, M., Schwingenschlögl-Maisetschläger, V., Holzer, W., ... & Pichler, V. (2023). Design, synthesis and preclinical evaluation of muscarine receptor antagonists via a scaffold-hopping approach. European Journal of Medicinal Chemistry, 262, 115891.