MRPL42 Polyclonal Antibody Reactivity Human
SKU: E-AB-53040-200
MRPL42 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53040 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human MRPL42 |
| Abbre | MRPL42 |
| Synonyms | 28S ribosomal protein S32, 39S ribosomal protein L31, 39S ribosomal protein L42, HSPC204 , L31mt, L42mt, MRP L31, MRP L42, MRP S32 , MRP-L31, MRP-L42, MRP-S32, MRPL31 , MRPS32, Mitochondrial ribosomal protein L42, Mitochondrial ribosomal protein S32, Mrpl42, mitochondrial |
| Swissprot | |
| Calculated MW | 17 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Mitochondrion. |
| Concentration | 1.02 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.