MKS1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52922-200
MKS1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52922 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human MKS1 |
| Abbre | MKS1 |
| Synonyms | B8d3, BBS13, Dysencephalia splanchnocystica, FABB proteome like protein, FLJ20345, Gruber syndrome, Meckel gruber syndrome, Meckel gruber syndrome type 1, Meckel syndrome, Meckel syndrome type 1, Meckel syndrome type 1 protein, Meckel syndrome type 1 protein homolog |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton>cilium basal body. Cytoplasm>cytoskeleton>microtubule organizing center>centrosome. Localizes at the transition zone, a region between the basal body and the ciliary axoneme. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Tags, Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.