LZTFL1 Polyclonal Antibody Store at -20°C
SKU: E-AB-11375-200
LZTFL1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11375 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human LZTFL1 |
| Abbre | LZTFL1 |
| Synonyms | 5530402H04Rik, 6130400H19Rik, AI414725, AW048545, BBS17, DKFZp686H2076, FLJ36386, LZTFL 1, Leucine zipper transcription factor like 1, Leucine zipper transcription factor like protein 1, Leucine zipper transcription factor-like protein 1, Lztfl1, Lztfl1 leucine zippe |
| Swissprot | |
| Calculated MW | 35 kDa |
| Cellular Localization | Cytosol |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.