LIPA Polyclonal Antibody Reactivity Human
SKU: E-AB-52935-200
LIPA Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52935 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human LIPA |
| Abbre | LIPA |
| Synonyms | cholesterol est, lysosomal acid, Acid cholesteryl ester hydrolase, CESD, Cholesteryl esterase, Hydrolase deficiency, LAL, LAL deficiency cholesterol ester, LICH, LIPA deficiency, Lipase A, cholesterol ester hydrolase, cholesterol ester storage disease, lipA, lipase A |
| Swissprot | |
| Cellular Localization | Lysosome. |
| Concentration | 0.72 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene.