ITGA2B Polyclonal Antibody Store at -20°C
SKU: E-AB-15138-200
ITGA2B Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15138 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ITGA2B |
| Abbre | ITGA2B |
| Synonyms | BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GPalpha IIb, GT, GTA, HPA3, ITA2B, ITGAB, Integrin, Integrin alpha 2b, Integrin alpha IIb, Integrin alpha-IIb light chain, Itga2b, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41, antigen CD41), form 2, platelet |
| Swissprot | |
| Calculated MW | 113 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.