IDH3G Polyclonal Antibody Store at -20°C
SKU: E-AB-14638-200
IDH3G Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14638 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human IDH3G |
| Abbre | IDH3G |
| Synonyms | H IDHG, IDH gamma, IDH3G, Isocitrate dehydrogenase 3 (NAD+) gamma, Isocitrate dehydrogenase [NAD] subunit gamma, Isocitric dehydrogenase, Isocitric dehydrogenase subunit gamma, NAD (H, mitochondrial |
| Swissprot | |
| Calculated MW | 43 kDa |
| Cellular Localization | Mitochondrion. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic.NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle.Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.