HYAL2 Polyclonal Antibody Store at -20°C
SKU: E-AB-11315-200
HYAL2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11315 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HYAL2 |
| Abbre | HYAL2 |
| Synonyms | HYAL2, Hyal 2, Hyal-2, Hyal2, Hyaluronidase 2, Hyaluronidase 2 Precursor, Hyaluronidase-2, Hyaluronoglucosaminidase 2, Hyaluronoglucosaminidase-2, LUCA 2, LUCA-2, LUCA2, Lung carcinoma protein 2, PH 20 homolog, PH-20 homolog, PH20 homolog, lysosomal hyaluronidase |
| Swissprot | |
| Cellular Localization | Cell membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.