HSP70 Polyclonal Antibody Reactivity Human
SKU: E-AB-40490-200
HSP70 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-40490 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of Human Heat shock 70 kDa protein 1A |
| Abbre | HSP70 |
| Synonyms | HSP70-1B, HSP70-2, HSP70.2, heat shock protein family A (Hsp70) member 1B, heat shock protein family A (Hsp70) member 1A |
| Swissprot | |
| Calculated MW | 64,70 kDa |
| Observed MW | 70 kDa |
| Cellular Localization | Cytoplasm, Cytoskeleton, Nucleus, Secreted. |
| Tissue Specificity | By heat shock |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:2000-1:10000 |
Background
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.