HMB-45 Monoclonal Antibody Stored at -20°C
SKU: ELAB6942-M-0.1
HMB-45 Monoclonal Antibody Stored at -20°C
Product Details
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | HMB-45 |
| Cellular Localization | Cytoplasm |
| Tissue Specificity | melanoma |
| Storage | The concentrated should be stored at -20°C protecting from light,Valid for 12 months. |
| Shipping | Ice bag |
Background
HMB45 is a melanoma-associated antigen that is mainly expressed in immature melanocytes. It was also expressed in activated and neoplastic melanocytes and other neural crest-derived tumors. It was also expressed in normal breast epithelium, some normal sweat glands, sweat gland-derived tumors and angiomyolipoma, and occasionally in carcinoma. "It is more specific than S-100 or NKl/C3 for the diagnosis of malignant melanoma, but the sensitivity is less than 90%, especially in metastatic melanoma."