GPM6A Polyclonal Antibody Store at -20°C
SKU: E-AB-10938-200
GPM6A Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10938 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human GPM6A |
| Abbre | GPM6A |
| Synonyms | GPM6A, M6a, Neuronal membrane glycoprotein M6-a |
| Swissprot | |
| Calculated MW | 31 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:200 |
Background
Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene.Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells.Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation.GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways.May be involved in neuronal NGF-dependent Ca2+ influx.May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.