GMDS Polyclonal Antibody Reactivity Human
SKU: E-AB-52916-200
GMDS Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52916 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human GMDS |
| Abbre | GMDS |
| Synonyms | 6 dehydratase, GDP D mannose dehydratase, GDP mannose 4 6 dehydratase, GDP-D-mannose dehydratase, GDP-mannose 4, GMD, GMDS, Gmds, OTTHUMP00000017756, OTTHUMP00000232770, SDR3E1, Short chain dehydrogenase/reductase family 3E member 1 |
| Swissprot | |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).