GFRA1 Polyclonal Antibody Store at -20°C
SKU: E-AB-15685-200
GFRA1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15685 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GFRA1 |
| Abbre | GFRA1 |
| Synonyms | GDNF R, GDNF RA, GDNF family receptor alpha 1, GDNF family receptor alpha-1, GDNF receptor alpha, GDNF receptor alpha-1, GDNFR, GDNFR alpha, GDNFR alpha 1, GDNFR-alpha-1, GDNFRA, GDNFRalpha, GFR alpha 1, GFR alpha1, GFR-alpha-1, GFRA 1, GFRA1, GFRalpha1, Gfra1, Glial cell l |
| Swissprot | |
| Calculated MW | 51 kDa |
| Cellular Localization | Cell membrane. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:3000 |
Background
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.