Galectin 3 Polyclonal Antibody Host Rabbit
SKU: E-AB-40380-200
Galectin 3 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40380 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Rat Galectin-3 protein |
| Abbre | Galectin 3 |
| Synonyms | 35 kDa lectin, CBP 35, CBP35, Carbohydrate binding protein 35, Carbohydrate-binding protein 35, GAL3, GALBP, GALIG, GBP, Gal-3, Galactose-specific lectin 3, Galactoside-binding protein, Galectin 3 internal gene, Galectin-3, Galectin3, IgE binding protein, IgE-bi, included |
| Swissprot | |
| Calculated MW | 27 kDa |
| Observed MW | 27 kDa |
| Cellular Localization | Cytoplasm, Nucleus, Secreted, Spliceosome. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Neuroscience, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:100 |
Background
Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth, adhesion, differentiation,apoptosis, angiogenesis,immune response, neoplastic transformation and metastasis .