FGFR1OP2 Polyclonal Antibody Store at -20°C
SKU: E-AB-11233-200
FGFR1OP2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11233 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human FGFR1OP2 |
| Abbre | FGFR1OP2 |
| Synonyms | DKFZp564O1863, FGFR1 oncogene partner 2, FGFR1OP2, FGOP2, Fibroblast growth factor receptor 1 oncogene partner 2, HSPC123, HSPC123 like, WIT3.0, Wound inducible transcript 3.0 |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin.Like other growth factors, FGFs act by binding and activating specific cell surface receptors which include the Flg receptor (FGFR-1) and the Bek receptor (FGFR-2), as well as FGFR-3, FGFR-4, FGFR-5 and FGFR-6.FGFR1OP2 (FGFR1 oncogene partner 2), also known as HSPC123, is a 253 amino acid cytoplasmic protein that is expressed in spleen, thymus and bone marrow and is involved in wound healing under normal cellular conditions.Additionally, FGFR1OP2 may also exist as an aberrant fusion protein with Flg and it is thought that the FGFR1OP2-Flg mutant may play a role in the pathogenesis of stem cell myeloproliferative disorder (MPD).Multiple isoforms of FGFR1OP2 exist due to alternative splicing events.