ERAL1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52749-200
ERAL1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52749 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ERAL1 |
| Abbre | ERAL1 |
| Synonyms | CEGA, Conserved ERA like GTPase, Conserved ERA-like GTPase, ERA, ERA W, ERA-W, ERA-like protein 1, ERAL1, ERAL1A, ERAW, Era (E.coli G protein homolog) like 1, Era G protein like 1, Era G protein like 1 (E.coli), Eral1, GTP binding protein era homolog, GTPase , GTPase Era |
| Swissprot | |
| Calculated MW | 48 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Membrane, Mitochondrion, Mitochondrion inner membrane. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.