DSC2 Polyclonal Antibody Store at -20°C
SKU: E-AB-13194-200
DSC2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13194 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human DSC2 |
| Abbre | DSC2 |
| Synonyms | ARVD11, CDHF2, Cadherin family member 2, DG2, DGII/III, DKFZp686I11137, DS, DSC 2, DSC2, Desmocollin 3, Desmocollin-2, Desmocollin-3, Desmocollin2, Desmosomal glycoprotein II, Desmosomal glycoprotein II and III, Desmosomal glycoprotein II/III, Desmosomal glycoprotein III |
| Swissprot | |
| Cellular Localization | Cell membrane. Cell junction>desmosome. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.