CYP11B1 Polyclonal Antibody Store at -20°C
SKU: E-AB-14911-200
CYP11B1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14911 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CYP11B1 |
| Abbre | CYP11B1 |
| Synonyms | CPN1, CYP11B, CYPXIB1, Cytochrome P 450c11, Cytochrome P450, Cytochrome P450 11B1, Cytochrome p450 XIB1, family 11, mitochondrial, pol, polypeptide 1, subfamily B, subfamily XIB, subfamily XIB (steroid 11 beta hydroxylase) |
| Swissprot | |
| Cellular Localization | Mitochondrion inner membrane. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.