CLTB Polyclonal Antibody Reactivity Human
SKU: E-AB-53085-200
CLTB Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53085 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CLTB |
| Abbre | CLTB |
| Synonyms | Light Chain (Lcb), Light Chain B., Light Polypeptide (Lcb), Clathrin, Clathrin Light Chain B, LCB |
| Swissprot | |
| Calculated MW | 25 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytosol, Golgi apparatus, clathrin coat of trans-Golgi network vesicle, trans-Golgi network, Plasma Membrane, ciliary membrane, clathrin coat of coated pit, plasma membrane, Other locations: clathrin coat, clathrin vesicle coat, clathrin-coated endocytic vesicle, intracellular membrane-bounded organelle. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. The clathrin molecule has a triskelion shape. Each clathrin triskelion is composed of three identical heavy chains (180 kDa) and three light chains of two types,LCA (CLTA) and LCB (CLTB) (30-40 kDa). The light chain subunits are thought to regulate the formation or disassembly of clathrin coats.