Chromogranin A Polyclonal Antibody Host Rabbit
SKU: E-AB-40339-200
Chromogranin A Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40339 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Mouse Chromogranin-A protein |
| Abbre | Chromogranin A |
| Synonyms | CHG A, CMGA, CgA, Chga, Chromogranin A, Chromogranin A parathyroid secretory protein 1, Chromogranin A precursor, ChromograninA, ER-37, Pancreastatin, Parastatin, Parathyroid secr, beta Granin, betagranin (N-terminal fragment of chromogranin A), catestatin, chromofungin |
| Swissprot | |
| Calculated MW | 51 kDa |
| Observed MW | 51 kDa |
| Cellular Localization | Cytoplasmic vesicle, Membrane, Secreted. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:1000 |
| IHC | 1:100-1:300 |
Background
Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) ,and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.