CES2 Polyclonal Antibody
SKU: E-AB-19698-200
CES2 Polyclonal Antibody
| SKU # | E-AB-19698 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CES2 |
| Abbre | CES2 |
| Synonyms | CE-2, CES2, CES2A1, Carboxylesterase 2, Carboxylesterase 2 (intestine, Cocaine esterase, EC 3.1.1.1, EST2, ICE, Iintestinal carboxylesterase liver carboxylesterase 2, Intestinal carboxylesterase, Methylumbelliferyl acetate deace, hCE-2, liver carboxylesterase-2, liver) |
| Swissprot | |
| Calculated MW | 62 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Endoplasmic reticulum lumen. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.