CENPU Polyclonal Antibody
SKU: E-AB-11402-200
CENPU Polyclonal Antibody
| SKU # | E-AB-11402 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CENPU |
| Abbre | CENPU |
| Synonyms | CENP U, CENP-50, CENP-U, CENP50, CENPU, CENPU50, Centromere protein U, FLJ23468, HHV8 LNAIP1, ICEN24, Interphase centromere complex protein 24, KLIP-1, KLIP1, KS, Kaposi Sarcoma Herpesvirus latent nuclear antigen interacting protein 1, centromere protein of 50 kDa |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Chromosome>centromere>kinetochore. Localizes in the kinetochore domain of centromeres. Colocalizes with PLK1 at the interzone between the inner and the outer kinetochore plates. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Microbiology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly.