CDC27 Polyclonal Antibody Store at -20°C Host Rabbit
SKU: E-AB-16327-200
CDC27 Polyclonal Antibody Store at -20°C Host Rabbit
| SKU # | E-AB-16327 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CDC27 |
| Abbre | CDC27 |
| Synonyms | ANAPC3, APC 3, APC3, Anaphase Promoting Complex 3, Anaphase Promoting Complex Subunit 3, Anaphase promoting complex protein 3, Anaphase-promoting complex subunit 3, CDC27, CDC27 homolog, CDC27Hs, Cdc 27, Cdc27, Cell Division Cycle 27, Cell division cycle protein 27 ho |
| Swissprot | |
| Calculated MW | 92 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | WB 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.